GENERAL CATALOGUE
A-62198
HY-129737 · 50 mg
MedChemExpress · Cat: HY-129737
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Catalog No: HY-129737
CAS No: 117978-26-4
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
A-62198 is a potent and selective renin inhibitor with antihypertensive activity. A-62198 reduces mean arterial pressure MAP in anesthetized, salt-deprived monkeys in a dose-dependent manner. A-62198 induced MAP reduction in normal monkeys that reached statistical significance at the highest dose and significantly inhibited plasma renin activity PRA at all doses.