GENERAL CATALOGUE
A-9758
HY-126252 · 50 mg
MedChemExpress · Cat: HY-126252
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medchemexpress.com/a-9758.htmlCatalog No: HY-126252
CAS No: 2055271-22-0
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
A-9758 is a ROR? ligand and a potent, selective ROR?t inverse agonist IC50=5 nM , and exhibits robust potency against IL-17A release. A-9758 is effective in suppressing both Th17 differentiation and Th17 effector function. A-9758 significantly attenuates IL-23 driven psoriasiform dermatitis and is effective in blocking skin and joint inflammation.