GENERAL CATALOGUE
AAT-008
HY-122168 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-122168
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Catalog No: HY-122168
CAS No: 847727-81-5
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
AAT-008 is a potent, selective, and orally active prostaglandin EP4 receptor antagonist with Kis of 0.97 and 6.1 nM for recombinant human EP4 and recombinant rat EP4, respectively. AAT-008 exerts tumor growth delay in mice bearing CT26WT colon tumors when combined with radiotherapy. AAT-008 can be used for the study of acute and chronic inflammatory pain and cancer .
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