GENERAL CATALOGUE
ABBV-744
HY-112090 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-112090
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Catalog No: HY-112090
CAS No: 2138861-99-9
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with agent-like properties enable the investigation of its antitumor efficacy and tolerability.
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