ABCA1 Mouse Monoclonal Antibody

Description

EnkiLife offers the ABCA1 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Rabbit,Monkey species and is suitable for IHC,ICC,FC application. Alternative Names of Immunogen: TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:100-1:500,ICC 1:200-1:1000,FC 1:200-1:400 Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.