ABL2 Stable Ba/F3 Cell Line

Name: ABL2 Stable Ba/F3 Cell Line
Brand: abm good

T3101 · 1 x 106 cells / 1.0 mL

abm good · Cat: T3101

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Catalog No: T3101

Category: Cellular Materials

Pack Size: 1 x 106 cells / 1.0 mL

Brand: abm good

Description

Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The ABL2 Stable Ba/F3 Cell Line expresses activated human ABL2 tyrosine kinase that is linked to a GFP reporter GFP-ETV6-ABL2 in SED2 vector . Ba/F3 cells expressing activated tyrosine kinase become completely dependent on the kinase activity for survival and as a result, the cells can be propagated even in the absence of IL-3. This cell line carries the SED2 vector which does not have any selection markers.