GENERAL CATALOGUE
Abrocitinib
HY-107429 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-107429
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medchemexpress.com/Abrocitinib.html
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Catalog No: HY-107429
CAS No: 1622902-68-4
Category: Epigenetics
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Abrocitinib PF-04965842 is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib PF-04965842 exhibits less active effect on TYK2 IC50, 1.253 ?M , and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease.
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