

HY-107429R · 1 mg
MedChemExpress · Cat: HY-107429R
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Manufacturer product page
medchemexpress.com/abrocitinib-standard.html
Description
Abrocitinib Standard is the analytical standard of Abrocitinib. This product is intended for research and analytical applications. Abrocitinib PF-04965842 is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib PF-04965842 exhibits less active effect on TYK2 IC50, 1.253 ?M , and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease.

