GENERAL CATALOGUE
AC-4-130
HY-124500 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-124500
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Manufacturer product page
medchemexpress.com/ac-4-130.htmlCatalog No: HY-124500
CAS No: 1834571-82-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AC-4-130 is a potent STAT5 SH2 domain inhibitor. AC-4-130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5-dependent gene transcription. AC-4-130 induces cell cycle arrest and apoptosis in FLT3-ITD-driven leukemic cells. AC-4-130 has anti-cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia AML .
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