GENERAL CATALOGUE
Ac-Exatecan
HY-79490 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-79490
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Catalog No: HY-79490
CAS No: 2922852-48-8
Category: Antibody-drug Conjugate ADC Related
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Ac-Exatecan is acetylation-modified Exatecan HY-13631 . Exatecan is a common toxin component in ADC preparation ADC cytotoxin and an inhibitor of DNA topoisomerase I IC50 = 2.2 ?M . Exatecan has antitumor activity. Exatecan can be used as a payload for ADC. Exatecan is effective against P-glycoprotein mediated multi-drug resistant cells.
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