

HY-P1169A · 50 mg
MedChemExpress · Cat: HY-P1169A
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Manufacturer product page
medchemexpress.com/ac-ietd-afc-tfa.html
Description
Ac-IETD-AFC TFA is a synthetic fluorogenic substrate that can be used to specifically detect caspase-8 activity. INDO 1 pentasodium is imbued with the fluorophore AFC 7-amino-4-trifluoromethylcoumarin . When caspase-8 recognizes and cleaves the amide bond following the IETD sequence in this substrate, AFC is released and emits fluorescence Ex = 400 nm; Em = 505 nm .







