GENERAL CATALOGUE
Ac5GalNTGc epimer
HY-160109A · 5 mg
MedChemExpress · Cat: HY-160109A
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Catalog No: HY-160109A
CAS No: 1334320-77-2
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
Ac5GalNTGc epimer is an analogue of hexosamine and the racemate of Ac5GalNTGc HY-160109 . Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research.
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