GENERAL CATALOGUE
Acalabrutinib-d3
HY-W757743 · 1 mg
MedChemExpress · Cat: HY-W757743
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medchemexpress.com/acalabrutinib-d3.htmlCatalog No: HY-W757743
Pack Size: 1 mg
Brand: MedChemExpress
Description
Acalabrutinib-d3 ACP-196-d3 is the deuterated form of Acalabrutinib HY-17600 . Acalabrutinib ACP-196 is an orally active, irreversible, highly selective second-generation BTK inhibitor. Acalabrutinib covalently binds to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib shows strong targeting and efficacy in mouse models of chronic lymphocytic leukemia CLL .