GENERAL CATALOGUE
AChE/GSK-3?-IN-1
HY-150537 · 50 mg
MedChemExpress · Cat: HY-150537
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Catalog No: HY-150537
CAS No: 2412364-73-7
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
AChE/GSK-3?-IN-1 compound GT15 is a potent, dual AChE/GSK-3? inhibitor with IC50 values of 1.2, 149.8 and 22.4 nM for hAChE , hBChE and hGSK-3?, respectively. AChE/GSK-3?-IN-1 penetrates the blood-brain barrier BBB . AChE/GSK-3?-IN-1 has high kinase selectivity profiles for the CMGC kinase family. AChE/GSK-3?-IN-1 occupies the ATP binding site of DYRK1A. AChE/GSK-3?-IN-1 inhibits ROS expression and reduces oxidative stress. AChE/GSK-3?-IN-1 can be used for AlzheimerAAasAasAas disease research.
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