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Actinomycin D
ab291108 · 5 mg
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Catalog No: ab291108
Category: Reagents and Controls
Pack Size: 5 mg
Brand: abcam
Description
Actinomycin D a291108, previously known as 1036 is an antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines
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