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AD-2646
GENERAL CATALOGUE

AD-2646

HY-124134 · 50 mg

MedChemExpress · Cat: HY-124134

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medchemexpress.com/ad-2646.html
Catalog No: HY-124134
CAS No: 366487-89-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

AD-2646 LCL102 , a ceramide analog, can kill leukemic T cells EC50: 40 ?M . AD-2646 triggers the cleavage of caspase-8, -9 and -3, as well as the caspase substrate PARP. AD-2646 is a ceramidase inhibitor. AD-2646 induces an accumulation of endogenous ceramide owing to perturbed ceramide metabolism.

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