

HY-124134 · 50 mg
MedChemExpress · Cat: HY-124134
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medchemexpress.com/ad-2646.htmlDescription
AD-2646 LCL102 , a ceramide analog, can kill leukemic T cells EC50: 40 ?M . AD-2646 triggers the cleavage of caspase-8, -9 and -3, as well as the caspase substrate PARP. AD-2646 is a ceramidase inhibitor. AD-2646 induces an accumulation of endogenous ceramide owing to perturbed ceramide metabolism.







