Adcy7 CRISPR Knockout RIN-m Stable Cell Line (RIN-m-/-Adcy7)

Description

The Adcy7 Double Knockout RIN-m Stable Cell Line RIN-m -/-Adcy7 is derived from the RIN-m rat insulinoma line with a targeted deletion of both alleles of the adenylate cyclase 7 Adcy7 gene, pivotal in the cAMP signaling pathway. Generated using CRISPR/Cas9 genome editing technology, this cell line is an essential model for studying the impact of Adcy7 on insulin secretion and beta-cell function, offering valuable insights into diabetes research. By facilitating the exploration of cAMP-dependent pathways in pancreatic cells, it supports the identification of new therapeutic targets for diabetes management, ensuring consistent and reproducible results due to its stable genetic modification.