Adenosine A1-R Rabbit Polyclonal Antibody

Description

EnkiLife offers the Adenosine A1-R Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB,ICC/IF,ELISA application. Alternative Names of Immunogen: ADORA1; Adenosine receptor A1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000 Background: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008],function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family., Research Area: Neuroactive ligand-receptor interaction;