

HY-145785 · 50 mg
MedChemExpress · Cat: HY-145785
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Manufacturer product page
medchemexpress.com/adh-6.html
Description
ADH-6 is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53s transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases 1 .







