GENERAL CATALOGUE
ADH-6 TFA
HY-145785A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-145785A
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medchemexpress.com/adh-6-tfa.htmlCatalog No: HY-145785A
CAS No: 2990065-87-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
ADH-6 TFA is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53s transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential for the research of cancer diseases.