(+)-Adomeglivant

Description

+ -Adomeglivant + -LY2409021 is a potent and selective glycogenotropin receptor antagonist with glucose-lowering activity. + -Adomeglivant reduces fasting blood glucose levels in both healthy subjects and patients with type 2 diabetes. The use of + -Adomeglivant can help investigate the mechanisms of hyperglycemia in type 2 diabetes. The antagonistic effect of + -Adomeglivant makes it challenging to assess the metabolic consequences of postprandial hyperglycemia.