GENERAL CATALOGUE
AES-350
HY-138831 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-138831
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/aes-350.html
Sponsored
Catalog No: HY-138831
CAS No: 847249-57-4
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 ?M and 0.035 ?M, respectively. AES-350 is also against HDAC3, HDAC8 in an enzymatic activity assay with IC50 values of 0.187 ?M and 0.245 ?M, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia AML research.