GENERAL CATALOGUE
AF3485
HY-118184 · 1 mg
MedChemExpress · Cat: HY-118184
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Catalog No: HY-118184
CAS No: 1195786-61-8
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
AF3485 is a human mPGES-1 inhibitor that exhibits antitumor activity in vitro and in vivo. AF3485 inhibits tumor-associated angiogenesis by reducing PGE2 production, inhibiting EGFR signaling, and decreasing VEGF and FGF-2 expression. AF3485 reduced tumor growth in mice bearing human A431 xenograft tumors by subchronic administration.
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