Afatinib dimaleate (Standard)

Description

Afatinib dimaleate Standard is the analytical standard of Afatinib dimaleate . This product is intended for research and analytical applications. Afatinib BIBW 2992 dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family EGFR and HER2 , with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma ESCC , non-small cell lung cancer NSCLC and gastric cancer.