GENERAL CATALOGUE
Afatinib
HY-10261 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10261
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medchemexpress.com/Afatinib.html
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Catalog No: HY-10261
CAS No: 850140-72-6
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Afatinib BIBW 2992 is an orally active, potent and irreversible dual specificity inhibitor of ErbB family EGFR and HER2 , with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma ESCC , non-small cell lung cancer NSCLC and gastric cancer.
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