GENERAL CATALOGUE
Afimetoran
HY-139567 · 5 mg
MedChemExpress · Cat: HY-139567
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Catalog No: HY-139567
CAS No: 2171019-55-7
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Afimetoran BMS-986256 is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran BMS-986256 can inhibit TLR7/8 activation of the NF-?B pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells pDCs . Afimetoran BMS-986256 can be used for research on inflammation and autoimmune diseases systemic lupus erythematosus .