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AFM-30a hydrochloride
GENERAL CATALOGUE

AFM-30a hydrochloride

HY-125099A · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-125099A

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Catalog No: HY-125099A
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

AFM-30a hydrochloride is a potent protein arginine deiminase 2 PAD2 inhibitor and has excellent PAD2-selectivity. AFM-30a hydrochloride binds to PAD2 with an EC50 value of 9.5 ?M. AFM-30a hydrochloride also inhibits H3 citrullination with an EC50 value of 0.4 ?M. AFM-30a hydrochloride can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis RA , multiple sclerosis, lupus, and ulcerative colitis.

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