GENERAL CATALOGUE
AG-012986
HY-119715 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-119715
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Manufacturer product page
medchemexpress.com/ag-012986.htmlCatalog No: HY-119715
CAS No: 486414-35-1
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
AG-012986 is a multitargeted CDK inhibitor. AG-012986 is active against CDK1/2/4/6/5/9, with Kis of 9.2 nM CDK4/cyclin , 94 nM CDK2/cyclin A , and 44 nM CDK1/cyclin B , IC50s of 4 nM CDK9/cyclin T and 22 nM CDK5/p35 . AG-012986 has antiproliferative activities against cancer cells. AG-012986 induces cell cycle arrest, and apoptosis.
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