GENERAL CATALOGUE
AG-494
HY-101042 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-101042
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Catalog No: HY-101042
CAS No: 133550-35-3
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
AG-494 Tyrphostin AG 494 is a potent and selective EGFR tyrosine kinase inhibitor IC50=0.7 ?M . AG-494 inhibits the autophosphorylation of EGFR, ErbB2, HER1-2 and PDGF-R with IC50s 1.1, 39, 45 and 6 ?M, respectively. AG-494 blocks Cdk2 activation and inhibits EGF-dependent DNA synthesis.
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