GENERAL CATALOGUE
AG01
HY-P991664 · 1 mg
MedChemExpress · Cat: HY-P991664
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Catalog No: HY-P991664
Category: MAPK ERK Pathway
Pack Size: 1 mg
Brand: MedChemExpress
Description
AG01 is a monoclonal antibody against progranulin GP88 . AG01 inhibits triple-negative breast cancer TNBC cell proliferation and migration, reduces the expression of phosphorylated protein kinases p-Src, p-AKT, and p-ERK, and reduces the expression of oncogenic proteins such as Axl, c-MET, HIF-1?, and VEGF. AG01 inhibits tumor growth and Ki67 expression in a TNBC xenograft mouse model. AG01 can be used in the research of TNBC and other cancers.