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(+/-)-Aiphanol
GENERAL CATALOGUE

(+/-)-Aiphanol

HY-152120 · 50 mg

MedChemExpress · Cat: HY-152120

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Catalog No: HY-152120
CAS No: 578020-29-8
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

AAasAasAA+/- -Aiphanol is a newly discovered stilbenolignan analog. AAasAasAA+/- -Aiphanol exhibits significant anti-inflammatory activity, acting through inhibition of COX-1 and COX-2. The inhibitory effect on COX-1 IC50 = 1.9 ?M is particularly strong, while the effect on COX-2 IC50= 9.9 ?M is relatively weak. AAasAasAA+/- -Aiphanol effectively inhibits VEGFR2 IC50=0.92 ?M . AAasAasAA+/- -Aiphanol blocks angiogenesis and promotes apoptosis through inhibition of VEGFR2 and COX2 activity. AAasAasAA+/- -Aiphanol is orally active.

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