GENERAL CATALOGUE
AJI-214
HY-164455 · 50 mg
MedChemExpress · Cat: HY-164455
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medchemexpress.com/aji-214.htmlCatalog No: HY-164455
CAS No: 1395886-20-0
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
AJI-214 is a dual-target inhibitor of Aurora kinase A and JAK2. AJI-214 directly blocks Aurora kinase A to inhibit T cell mitotic progression and cell polarity, and inhibits JAK2 activation to inhibit STAT3 phosphorylation, thereby reducing the differentiation of TH1 and TH17 cells. AJI-214 can be used in studies on regulating immune responses and preventing graft-versus-host disease GVHD .
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