AKAP 2 Rabbit Polyclonal Antibody

Description

EnkiLife offers the AKAP 2 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,ELISA application. Alternative Names of Immunogen: AKAP2; KIAA0920; PRKA2; A-kinase anchor protein 2; AKAP-2; AKAP-KL; Protein kinase A-anchoring protein 2; PRKA2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:10000-1:20000 Background: The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],caution:It is uncertain whether Met-1 or Met-3 is the initiator.,function:Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP.,miscellaneous:Can be differentially expressed as a natural AKAP2-PALM2 chimeric protein.,similarity:Belongs to the paralemmin family.,tissue specificity:Expressed in infantile heart and muscle, and fibroblasts.,