

HY-118304B · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-118304B
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medchemexpress.com/akn-028-acetate.htmlDescription
AKN-028 acetate, a novel tyrosine kinase TK inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 FLT3 inhibitor with an IC50 value of 6 nM. AKN-028 acetate inhibits FLT3 autophosphorylation. AKN-028 acetate induces dose-dependent cytotoxic response mean IC50=1 ?M . AKN-028 acetate induces apoptosisby activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia AML .







