GENERAL CATALOGUE
AKN-028 TFA
HY-118304A · 50 mg
MedChemExpress · Cat: HY-118304A
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medchemexpress.com/akn-028-tfa.html
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Catalog No: HY-118304A
CAS No: 1175017-91-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
AKN-028 TFA, a novel tyrosine kinase TK inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 FLT3 inhibitor with an IC50 value of 6 nM. AKN-028 TFA inhibits FLT3 autophosphorylation. AKN-028 TFA induces dose-dependent cytotoxic response mean IC50=1 ?M . AKN-028 TFA induces apoptosisby activation of caspase 3. AKN-028 TFA can be used in research of acute myeloid leukemia AML .
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