

HY-173453 · 50 mg
MedChemExpress · Cat: HY-173453
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medchemexpress.com/akr1c3-in-15.html
Description
AKR1C3-IN-15 compound 30 is a potent and selective AKR1C3 inhibitor with an IC50 of 5 nM. AKR1C3-IN-15 enhances Sorafenib HY-10201 -induced ROS generation, promoted apoptosis, and restored sorafenib sensitivity in HCC models both in vitro and in vivo.