GENERAL CATALOGUE
AKT-IN-3
HY-126257 · 5 mg
MedChemExpress · Cat: HY-126257
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medchemexpress.com/akt-in-3.htmlCatalog No: HY-126257
CAS No: 2374740-21-1
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
AKT-IN-3 compound E22 is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 compound E22 also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 compound E22 induces apoptosis and inhibits metastasis of cancer cells.
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