GENERAL CATALOGUE
AL-GDa62
HY-145269 · 50 mg
MedChemExpress · Cat: HY-145269
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medchemexpress.com/al-gda62.htmlCatalog No: HY-145269
CAS No: 2761538-66-1
Category: Cytoskeleton
Pack Size: 50 mg
Brand: MedChemExpress
Description
AL-GDa62 is a derivative of the CDH1/E-cadherin modulator SLEC-11 HY-145268 and induces apoptosis in CDH1-/- cells. AL-GDa62 has an EC50 of 3.2 ?M and 2 ?M for isogenic mammary epithelial cells MCF10A-WT wild type and mutant MCF10A-CDH1-/-, respectively. AL-GDa62 specifically inhibits TCOF1, ARPC5, and UBC9, and suppresses SUMOylation at low micromolar concentrations.
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