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Alectinib-d8
GENERAL CATALOGUE

Alectinib-d8

HY-13011S · 1 mg

MedChemExpress · Cat: HY-13011S

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medchemexpress.com/alectinib-d8.html
Catalog No: HY-13011S
CAS No: 1256585-15-5
Pack Size: 1 mg
Brand: MedChemExpress

Description

Alectinib-d8 is the deuterium labeled Alectinib. Alectinib CH5424802 is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM in an ATP-competitive manner , and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system CNS penetration.

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