GENERAL CATALOGUE
Alisertib
HY-10971 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10971
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Catalog No: HY-10971
CAS No: 1028486-01-2
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Alisertib MLN 8237 is an orally active and selective Aurora A kinase inhibitor IC50=1.2 nM , which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib MLN 8237 induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity.
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