GENERAL CATALOGUE
Alisertib sodium
HY-10971A · 50 mg
MedChemExpress · Cat: HY-10971A
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medchemexpress.com/alisertib-sodium.htmlCatalog No: HY-10971A
CAS No: 1028486-06-7
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Alisertib MLN 8237 sodium is an orally active and selective Aurora A kinase inhibitor IC50=1.2 nM , which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib sodium induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity.
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