GENERAL CATALOGUE
ALK/ROS1-IN-5
HY-170418 · 50 mg
MedChemExpress · Cat: HY-170418
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medchemexpress.com/alk-ros1-in-5.html
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Catalog No: HY-170418
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
ALK/ROS1-IN-5 compound X4 is a selective ALK and ROS1 kinases inhibitor with IC50s of 0.512 ?M ALK , 0.766 ?M ROS1 , respectively. ALK/ROS1-IN-5 inhibits H2228 cells with an IC50 of 0.034 ?M. ALK/ROS1-IN-5 induces cancer cells apoptosis in dose-dependent manner. ALK/ROS1-IN-5 effectively suppresses the expression of p-ALK and p-ERK in cancer cells 1 .
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