GENERAL CATALOGUE
Almonertinib mesylate
HY-112823A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-112823A
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medchemexpress.com/almonertinib-mesylate.html
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Catalog No: HY-112823A
CAS No: 2134096-06-1
Category: JAK STAT Signaling
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Almonertinib HS-10296 mesylate is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 IC50: 0.37, 0.29 and 0.21 nM, respectively , and is less effective against wild type 3.39 nM . Almonertinib mesylate is used for the research of the non-small cell lung cancer.
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