GENERAL CATALOGUE
Almorexant
HY-10805 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10805
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medchemexpress.com/almorexant.htmlCatalog No: HY-10805
CAS No: 871224-64-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Almorexant ACT 078573 is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM OX1 and 0.17 nM OX2 , respectively. Almorexant reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant totally blocked the intracellular Ca2+ signal pathway. Almorexant stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis.