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Almorexant hydrochloride
GENERAL CATALOGUE

Almorexant hydrochloride

HY-10805A · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-10805A

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Catalog No: HY-10805A
CAS No: 913358-93-7
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Almorexant ACT 078573 hydrochloride is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM OX1 and 0.17 nM OX2 , respectively. Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant hydrochloride totally blocked the intracellular Ca2+ signal pathway. Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis.

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