GENERAL CATALOGUE
Alosetron
HY-70050A · 5 mg
MedChemExpress · Cat: HY-70050A
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Catalog No: HY-70050A
CAS No: 122852-42-0
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
Alosetron GR 68755 is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron is used for the research of irritable bowel syndrome IBS . Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at 55 nM. Alosetron attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects.
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