Alosetron Hydrochloride (Standard)

Description

Alosetron Hydrochloride Standard is the analytical standard of Alosetron Hydrochloride . This product is intended for research and analytical applications. Alosetron Hydrochloride GR 68755C is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome IBS . Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at 55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects.