alpha 1 Fetoprotein Rabbit Polyclonal Antibody

Description

EnkiLife offers the alpha 1 Fetoprotein Rabbit Polyclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ELISA application. Alternative Names of Immunogen: Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000 Background: Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma . Research Area: Cancer