GENERAL CATALOGUE
ALR-27
HY-155408 · 50 mg
MedChemExpress · Cat: HY-155408
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medchemexpress.com/alr-27.htmlCatalog No: HY-155408
CAS No: 903639-13-4
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
ALR-27 is an antagonist of the 5-lipoxygenase 5-LOX activating protein FLAP and has anti-inflammatory activity. ALR-27 potently inhibits 5-LOX product formation 80 % in pro-inflammatory M1-MDM, with no significant direct inhibition of 5-LOX. ALR-27 not only reduces prostaglandin and leukotriene LT production in neutrophils but also increases the production of specialized prolytic mediators in specific human macrophage phenotypes.
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