GENERAL CATALOGUE
Alrizomadlin
HY-101518 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-101518
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medchemexpress.com/apg-115.htmlCatalog No: HY-101518
CAS No: 1818393-16-6
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Alrizomadlin APG-115 is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.